13 research outputs found

    Interoperabilidade entre modelos bim e aplicação PRONIC : reabilitação de um edifício público

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    Orientação: Maria João Serpa da Lança Falcão da Silva; co-orientação: Paula Margarida Marques CoutoO cenário económico mundial, cada vez mais globalizado, exige que o setor da Arquitetura, Engenharia, Construção e Operação (AECO) acompanhe a evolução tecnológica que os outros setores da economia apresentam. Já não é aceitável que uma área de grande representatividade na geração, direta e indireta de empregos e, consequentemente, no Produto Interno Bruto (PIB), ainda não seja um exemplo de qualidade e boa gestão de recursos materiais e humanos. Surge como uma necessidade que o setor passe a apresentar melhor estruturação, orientação e gestão para que assim se ganhe em qualidade e eficiência. Neste sentido, os processos colaborativos de criação e gestão de informação que proporcionem ao utilizador uma antecipação na deteção de erros, constrangimentos, sobreposições de elementos, testes de soluções construtivas e até mesmo avaliações de eficiência energética de edifícios, como o que acontece no caso do Building Information Modelling (BIM), tanto no âmbito da construção nova quanto na reabilitação, são fundamentais para o desenvolvimento do setor onde a competitividade é cada vez maior. O desenvolvimento de uma metodologia que aproveite as vantagens da modelação em BIM, trará ganhos muito relevantes para o setor AECO preenchendo as suas eventuais lacunas com conteúdos técnicos e económicos normalizados, voltados para o cenário nacional, retirados do Protocolo para Normalização da Informação Técnica da Construção (ProNIC), um projeto de investigação desenvolvido em Portugal que visa facilitar, organizar e padronizar toda a parte da produção de informação técnica exigida nos diferentes projetos e ainda, agregar para cada trabalho construtivo específico as melhores práticas construtivas e as normas técnicas aplicáveis a cada situação. A associação entre a metodologia BIM e o ProNIC que seja capaz de gerar, de uma forma simples e normalizada, toda a informação escrita e desenhada necessária à execução de um empreendimento, contribuirá em muito para a melhoria da qualidade no setor.The world economic scenario, increasingly globalized, requires that the Architecture, Engineering, Construction and Operation (AECO) sector follow the technological evolution present in other economy sectors. It is no longer acceptable that an area of great representativeness in the direct and indirect generation of jobs and, consequently, in the Gross Domestic Product (GDP), is still not an example of quality and good management of human and material resources. It arises as a necessity that the sector should present better structuring, orientation and management so that it gains in quality and efficiency. In this sense, creation and management of information collaborative processes that provide the user an anticipation in the detection of errors, constraints, overlapping elements, testing constructive solutions, and even energy efficiency assessments of buildings, such as Building Information Modelling (BIM), both in the field of new construction as in the field of rehabilitation, are fundamental for the development of the sector where competitiveness is increasing. The development of a methodology that takes advantage of the benefits of modeling in BIM, will bring very considerable gains for the AECO sector, filling its possible gaps with standardized technical and economic contents, geared to the national scenario, taken from the Protocol for Standardization of Technical Information Construction (ProNIC - Portuguese abbreviation), a research project developed in Portugal that aims to facilitate, organize and standardize all the production of technical information required in the different projects and also to aggregate for each specific construction work the best construction practices and technical standards applicable to each situation. The association between the BIM methodology and ProNIC is able to, in a simple and standardized way, generate all the written and drawn information required to the execution of a project, will contribute a lot for the improvement of quality in the sector

    DB-HERITAGE: A database of mortars composition and characteristics

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    Mortars are materials that are present in constructions from the antiquity to nowadays, being complex in terms of their constituents, incorporating traditions and techniques related to the local knowledge. Furthermore, mortar characteristics are also dependent of its role and use in a particular local and environment. The knowledge of the mortars constituents, characteristics and behavior in their specific conditions is important in several contexts, namely in terms of materials history and for better definition of conservation strategies. That knowledge, obtained by many different researchers and practitioners of the area, should be easily available for all the people who need it, both for research and for direct use in the field. This was the context of the DB-HERITAGE database project (http://dbheritage.lnec.pt/), which intends to build a repository for historical building materials, and a free-access IT-tool to collect the related data on this construction material, including from conservative interventions made on mortars applied on historic constructions. An overview of the database tools will be presented in this paper, exemplifying some of its outputs and potentialities related to historic mortars in different case studies in Portugal.authorsversionpublishe

    Long-term safety of COVID vaccination in individuals with idiopathic inflammatory myopathies: results from the COVAD study

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    Limited evidence on long-term COVID-19 vaccine safety in patients with idiopathic inflammatory myopathies (IIMs) continues to contribute to vaccine hesitancy. We studied delayed-onset vaccine adverse events (AEs) in patients with IIMs, other systemic autoimmune and inflammatory disorders (SAIDs), and healthy controls (HCs), using data from the second COVID-19 Vaccination in Autoimmune Diseases (COVAD) study. A validated self-reporting e-survey was circulated by the COVAD study group (157 collaborators, 106 countries) from Feb-June 2022. We collected data on demographics, comorbidities, IIM/SAID details, COVID-19 history, and vaccination details. Delayed-onset (> 7 day) AEs were analyzed using regression models. A total of 15165 respondents undertook the survey, of whom 8759 responses from vaccinated individuals [median age 46 (35-58) years, 74.4% females, 45.4% Caucasians] were analyzed. Of these, 1390 (15.9%) had IIMs, 50.6% other SAIDs, and 33.5% HCs. Among IIMs, 16.3% and 10.2% patients reported minor and major AEs, respectively, and 0.72% (n = 10) required hospitalization. Notably patients with IIMs experienced fewer minor AEs than other SAIDs, though rashes were expectedly more than HCs [OR 4.0; 95% CI 2.2-7.0, p < 0.001]. IIM patients with active disease, overlap myositis, autoimmune comorbidities, and ChadOx1 nCOV-19 (Oxford/AstraZeneca) recipients reported AEs more often, while those with inclusion body myositis, and BNT162b2 (Pfizer) recipients reported fewer AEs. Vaccination is reassuringly safe in individuals with IIMs, with AEs, hospitalizations comparable to SAIDs, and largely limited to those with autoimmune multimorbidity and active disease. These observations may inform guidelines to identify high-risk patients warranting close monitoring in the post-vaccination period

    Flares after COVID-19 infection in patients with idiopathic inflammatory myopathies: results from the COVAD study

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    COVID-19 breakthrough infections in type 1 diabetes mellitus: a cross-sectional study by the COVID-19 Vaccination in Autoimmune Diseases (COVAD) Group

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    COVAD survey 2 long-term outcomes: unmet need and protocol

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    Vaccine hesitancy is considered a major barrier to achieving herd immunity against COVID-19. While multiple alternative and synergistic approaches including heterologous vaccination, booster doses, and antiviral drugs have been developed, equitable vaccine uptake remains the foremost strategy to manage pandemic. Although none of the currently approved vaccines are live-attenuated, several reports of disease flares, waning protection, and acute-onset syndromes have emerged as short-term adverse events after vaccination. Hence, scientific literature falls short when discussing potential long-term effects in vulnerable cohorts. The COVAD-2 survey follows on from the baseline COVAD-1 survey with the aim to collect patient-reported data on the long-term safety and tolerability of COVID-19 vaccines in immune modulation. The e-survey has been extensively pilot-tested and validated with translations into multiple languages. Anticipated results will help improve vaccination efforts and reduce the imminent risks of COVID-19 infection, especially in understudied vulnerable groups

    COVID-19 vaccine safety during pregnancy and breastfeeding in women with autoimmune diseases: results from the COVAD study

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    Objectives: We investigated COVID-19 vaccine safety in pregnant and breastfeeding women with autoimmune diseases (AID) in the COVID-19 Vaccination in Autoimmune Diseases (COVAD) study. Methods: Delayed-onset (>7 days) vaccine-related adverse events (AE), disease flares (DF), and AID-related treatment modifications were analyzed upon diagnosis of AID versus healthy controls (HC) and the pregnancy/breastfeeding status at the time of at least one dose of vaccine. Results: Among the 9201 participants to the self-administered online survey, 6787 (73.8%) were women. Forty pregnant and 52 breastfeeding patients with AID were identified, of whom the majority had received at least one dose of COVID-19 vaccine (100% and 96.2%, respectively). AE were reported significantly more frequently in pregnant than in non-pregnant patients (overall AE 45% vs 26%, p= 0.01; minor AE 40% vs 25.9%, p= 0.03; major AE 17.5% vs 4.6%, p< 0.01), but no difference was found in comparison with pregnant HC. No difference was observed between breastfeeding patients and HC with respect to AE. Post-vaccination DF were reported by 17.5% of pregnant and 20% of breastfeeding patients, and by 18.3% of age- and disease-matched non-pregnant and non-breastfeeding patients (n = 262). All pregnant/breastfeeding patients who experienced a DF were managed with glucocorticoids; 28.6% and 20% of them required initiation or change in immunosuppressants, respectively. Conclusion: This study provides reassuring insights into the safety of COVID-19 vaccines administered to women with AID during the gestational and post-partum periods, helping overcome hesitant attitudes, as the benefits for the mother and the fetus by passive immunization appear to outweigh potential risks

    COVID-19 vaccine safety during the antenatal period in women with idiopathic inflammatory myopathies

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    Flares in IIMs and the timeline following COVID-19 vaccination: a combined analysis of the COVAD-1 and 2 surveys

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    COVAD survey 2 long-term outcomes: unmet need and protocol

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    Vaccine hesitancy is considered a major barrier to achieving herd immunity against COVID-19. While multiple alternative and synergistic approaches including heterologous vaccination, booster doses, and antiviral drugs have been developed, equitable vaccine uptake remains the foremost strategy to manage pandemic. Although none of the currently approved vaccines are live-attenuated, several reports of disease flares, waning protection, and acute-onset syndromes have emerged as short-term adverse events after vaccination. Hence, scientific literature falls short when discussing potential long-term effects in vulnerable cohorts. The COVAD-2 survey follows on from the baseline COVAD-1 survey with the aim to collect patient-reported data on the long-term safety and tolerability of COVID-19 vaccines in immune modulation. The e-survey has been extensively pilot-tested and validated with translations into multiple languages. Anticipated results will help improve vaccination efforts and reduce the imminent risks of COVID-19 infection, especially in understudied vulnerable groups
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